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Monday, December 1, 2014

Image Credit: www.thehindubusinessline.com
Researchers, including two from Indian-origin, have created new engineered platelets that copy and beat characteristic platelets at controlling bleeding.

Analysts at the University of California, Santa Barbara turned to the human body's own particular components for motivation in managing the fundamental and muddled methodology of coagulation.

By making nanoparticles that copy the shape, adaptability and surface science of the body's platelets, they found themselves able to quicken common mending methodologies while opening the route to helps and medications that can be tweaked to particular patient needs.

"This is a huge breakthrough in the improvement of manufactured platelets, and additionally in focused on medication conveyance," said Samir Mitragotri, chief UC Santa Barbara's Center for Bioengineering (CBE).

The platelet-like nanoparticles (PLNs) act much the same as their human partners and can be added to the blood stream to supply or enlarge the understanding's regular platelet supply, stemming the stream of blood and starting the recuperating procedure, while permitting doctors and different guardians to start or proceed with the important treatment.

Crisis circumstances can be brought under control speedier, wounds can recuperate all the more rapidly and patients can recoup with less intricacies, specialists said.

"We were really ready to render a 65 every penny diminish in bleeding time contrasted with no treatment," said graduate understudy analyst Aaron Anselmo, lead writer of the paper.
As indicated by Mitragotri and partners Stefano Menegatti and Sunny Kumar, the key lies in the PLNs' mimicry of the genuine article.

By copying the shape and adaptability of characteristic platelets, PLNs can likewise stream to the damage site and assemble there.

With surfaces functionalised with the same biochemical themes found in their human partners, these PLNs additionally can summon different platelets to the site and tie to them, expanding the possibilities of shaping that vital fitting.

The platelets are built to break down into the blood after their handiness has run out, minimizing intricacies that can emerge from crisis hemostatic methodology.

As indicated by Anselmo's examinations, for the same surface properties and shape, nanoscale particles can perform surprisingly better than micron-size platelets.

This engineering takes into consideration customisation of the particles with other restorative substances — meds, treatments and such — that patients with particular conditions may require.

"This innovation could address a plenty of clinical difficulties," said Scott Hammond, chief of UCSB's Translational Medicine Research Laboratories.

With optimisable PLNs, doctors would have the capacity to strike a fine harmony between anticoagulant help and wound mending in more established patients, by utilizing nanoparticles that can target where clumps are framing without activating undesirable bleeding.

Wednesday, March 19, 2014

Image Source: http://www.telegraph.co.uk
Design planner and model L'wren Scott has been discovered dead today (March 17) at her Manhattan home, she was 49 years old.
Scott, who was additionally the better half of Rolling Stone Mick Jagger, was discovered hanged in her 11th Avenue condo at 10am, as the police said.
A representative for Scott issued the accompanying explanation to Digital Spy: "We affirm the disastrous passing of L'wren Scott.
"At this destroying time for Ms. Scott's family and companions, we ask for that their security be regarded. There will be no further open proclamation for the present."
The head medicinal inspector's office is yet to focus a reason for death, however sources have said that police don't suspect treachery.
Scott, conceived Luann Bambrough, was said to have sent a content to an unidentified collaborator at around 8.30am, inciting officers to enter the loft.
Conceived in Utah, Scott functioned as a model in Paris before later turning into a big name beautician and design architect.
She planned Sharon Stone's attire for the 1996 redo of Diabolique, and counseled on Nicole Kidman's wardrobe for Stanley Kubrick's last film Eyes Wide Shut.
Scott additionally dealt with Martin Scorsese's Shine a Light - the executive's Rolling Stones show film - planning Jagger's attire for the band's 2008 'Greater Bang' tour.

Image Source: http://www.ft.com
Jagger's agent said: "He is completely shocked and crushed by the news." The vocalist is at present on tour in Perth, Australia.



Tuesday, March 11, 2014

The savage winter of 2013-14 so far has brought on practically $5 billion in harm to the country's homes, organizations, base and agribusiness, consistent with information from Aon Benfield, a worldwide reinsurance firm situated in London.

That is about $2 billion above normal.

Source: http://www.ctvnews.ca

"This has been a somewhat unreasonable and significant year for winter climate occasions in the United States," said Steve Bowen, Aon Benfield meteorologist and senior researcher.

The aggregate does not incorporate travel and transportation misfortunes or different business disturbance, in any case, which are liable to run into the "billions of dollars," Bowen said in an email.

Lost flights alone have as of recently cost aerial transports, runways and travelers an expected $5.8 billion, consistent with a report discharged not long ago by masflight, an expository gathering that studies flying operations.

Source: http://www.durangoherald.com

While the $5 billion harm aggregate is above the later 10-year normal and the most noteworthy since 2010-11, it doesn't rank as one of the costliest on record:

"In advanced times, 1993 remains the standard, given the hugeness of the 'Storm of the Century' in March of that year, which brought about $9 billion in harm alone," Bowen said.

An arrangement of winter storms a month ago carried overwhelming snowfall, slush, solidifying drizzle, ice, windy winds and severely cool Arctic air to the country. Two of the greatest storms executed no less than 34 individuals and brought about an expected $750 million in harm.

Source: http://www.financialpost.com

In spite of the surprisingly high harm fetches this winter, the toll is little contrasted and the expenses of catastrophes, for example, 2012's Hurricane Sandy (with an expense of $65 billion) and that year's Midwest/plains dry season ($35 billion), as per Aon Benfield information.

Last national climate information about how frosty and frigid the winter of 2013-14 really was (meteorologists characterize winter as the months of December, January and February) will be discharged by the National Climatic Data Center next Thursday.

Thursday, March 6, 2014



The first official trailer for Michael Bay's upcoming "Transformers: Age of Extinction" is finally here. And, unsurprisingly, it's very Michael Bay-esque.


A cash-strapped, patriotic mechanic (Mark Wahlberg) discovers that an old junker he found is actually a dormant Optimus Prime. The Transformers, as Stanley Tucci tells us, are outmoded and obsolete...until a new threat crash lands on Earth.
With former franchise star Shia LaBeouf off somewhere making weird performance art, it's up to Wahlberg and rising star Jack Reynor to aid Optimus and the Autobots in their ongoing battle against the Decepticons. Also joining the fray are the Dinobots, led by the slow-witted Grimlock (at least on the old cartoon). Plus, lots of explosions, muscles, babes, slow-motion and American flags. This is a Michael Bay movie, after all.



It also stars Sophia Myles, Kelsey Grammer, and Li Bingbing.


"Transformers: Age of Extinction" Action start on - June 27.

Courtesy: Hitfix.com

Tuesday, March 4, 2014

Time flies when you're a Hollywood superstar. Yet for these five well known entertainers, time is additionally on their side.

Examine a couple of in the not so distant future Academy Awards candidates posturing close by their younger selves. Meryl Streep stands floored as a youthful Meryl from 1979 holds her first Oscar gladly circulating everywhere. A recognized Leonardo Dicaprio puts an arm around his former bashful, boyish self. Furthermore Jennifer Lawrence essentially has a striking resemblance, aside from possibly a touch of modernity that accompanies a couple of additional years in the business.

It would appear to be these five superstars have scarcely matured a day. Tastes, style and particularly improved hairdos may have changed, yet they'll generally be the same youthful starlets on a basic level.


1. Jennifer Lawrence: 2008 and 2014


2. Leonardo DiCaprio: 1998 and 2014


3. Julia Roberts: 1991 and 2014


4. Matthew McConaughey: 2003 and 2014


5. Meryl Streep: 1979 and 2014


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